Although this endpoint may be of biologic importance in a disease-specific intervention, it is a more subjective endpoint than total mortality. 虽然这终点可能体现在疾病特定干涉的生物学重要性，但它是比总死亡率更为主观的终点。
Clinical study showed that in treatment of heart failure, bisoprolol is able to decrease the total and cardiovascular mortality, together with re-admission rate. 临床研究表明比索洛尔用于心力衰竭病人，可降低总死亡率和心血管死亡率，减少再入院发生率。
